San Lorenzo Vacations from $934

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your San Lorenzo Vacation

If you're wanting a food-lovers escape, our San Lorenzo vacation packages are what you need. Whether you want to experience its nightlife, bars and pubs or culture, this neighborhood has something on offer for everyone. Some top nearby attractions to visit during your trip to San Lorenzo include Roman Forum, Pantheon and Piazza Navona. Expedia can help you turn your ideal San Lorenzo vacation into reality, whatever your budget or travel plans.

The Latest San Lorenzo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

Nomentano
$934
per person
Nov 18 - Nov 22
found 21 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (323 reviews)
Hotel Le Petit

Hotel Le Petit

Rome City Centre
Save 100% on your flight
$1,285
per person
Nov 12 - Nov 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9/10 Wonderful! (20 reviews)
Hotel Le Petit was a really lovely room! The staff were super friendly and very helpful with booking transportation to the airport or helping with other things also! Would stay here again!

Reviewed on Oct 8, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$5,381
per person
Nov 21 - Nov 25
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (1,011 reviews)
Albergo Etico Roma

Albergo Etico Roma

Flaminio
$1,252
per person
Nov 24 - Nov 30
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.8/10 Exceptional! (379 reviews)
Corinthia Rome

Corinthia Rome

Rome City Centre
Save 100% on your flight
$2,837
per person
Dec 20 - Dec 24
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
10/10 Exceptional! (3 reviews)
A wonderful stay with elegant rooms, nice restaurant, attentive service, and thoughtful touches throughout. The staff made us feel welcome from arrival to departure. Would happily return.

Reviewed on Sep 11, 2026

Where to stay in San Lorenzo

Find the best San Lorenzo areas and neighborhoods for the activities you enjoy most. Learn more about San Lorenzo
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

San Lorenzo Hotel Deals

Líbere Rome San Lorenzo

Líbere Rome San Lorenzo

Via degli Ausoni, 33 Rome RM
Fully refundableReserve now, pay when you stay
$89 nightly
$111 total
Nov 9 - Nov 10
Total with taxes and fees
9.6/10 Exceptional! (53 reviews)
"We stayed at Hotel Liberté as a family of three during our trip to Rome. Overall, we had a nice stay and really liked the neighborhood. It has a young, hip and artsy feel, with lots of little bars, restaurants and about 15-20 mins walk on side street from Termini Station. If you enjoy that kind of ..."

Reviewed on Oct 3, 2026

Líbere Rome San Lorenzo
Fabulous Village

Fabulous Village

Via Di Malafede 225 Rome RM
$68 nightly
$81 total
Oct 12 - Oct 13
Total with taxes and fees
8.2/10 Very Good! (1,893 reviews)
"Great price for what you get. Clean place. Small, but workable for a family. Pool is great. Wifi in many areas. Decent food."

Reviewed on Oct 7, 2026

Fabulous Village
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

Via Portuense, 2465 Fiumicino RM
Fully refundableReserve now, pay when you stay
$153 nightly
$179 total
Nov 1 - Nov 2
Total with taxes and fees
8/10 Very Good! (2,117 reviews)
"Near the airport"

Reviewed on Oct 8, 2026

Best Western Hotel Rome Airport
See all 16,669 properties in San Lorenzo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Lorenzo attractions

Teatro Blackgull

Enjoy a performance at Teatro Blackgull, a theater with a story to tell in Rome. Visit the churches and notable monuments in this vibrant area.
See properties

Wishlist Club

After visiting Wishlist Club, make a plan to see the other sights and activities in Rome. Make time to visit the cathedral and monuments while you're in the area.
See properties

Lupa Romana

10.0/10 (1 review)
Enjoy an outing to Lupa Romana during your stay in Rome. Visit the notable monuments and stunning cathedral in this vibrant area.
See properties

Studio d'Arte Contemporanea di Pino Casagrande

You can study the exhibits at Studio d'Arte Contemporanea di Pino Casagrande, a museum with a storied past, during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
See properties

Pastificio Cerere

You can browse the exhibits at Pastificio Cerere, a museum with a story of its own, during your travels to Rome. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
See properties

Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$130
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
Pasta-Making Class: Cook, Dine & Drink With A Local Chef

Pasta-Making Class: Cook, Dine & Drink With A Local Chef

$54
per adult
100% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.